| Host: |
Rabbit |
| Applications: |
ELISA/WB/IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Neurturin is suitable for use in ELISA, Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Concentrated ammonium sulphate in PBS pH 7.4 |
| Purification: |
Immunogen affinity purification |
| Dilution Range: |
WB 0.2 to 1 µg/ml; ELISA 0.01 to 0.02 µg/ml; IF 0.5 to 2 µg/ml Antibody doesn t cross-react to other GDNF-family proteins Polyclonal antibody working titer has to be established practically for each particular antigen and assay format |
| Storage Instruction: |
Store at +4°C upon receipt. As product is (NH4) 2SO4 precipitate, mix well by pipetting or vortexing prior use |
| Gene Symbol: |
NRTN |
| Gene ID: |
4902 |
| Uniprot ID: |
NRTN_HUMAN |
| Specificity: |
Human NRTN |
| Immunogen: |
Recombinant human NRTN protein produced using CHO-based proprietary suspension cell line. Protein was purified from the cell culture supernatant. human Neurturin |
| Function | Growth factor that supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Involved in the development of the neural crest. Might control the size of non-neuronal cell population such as haemopoietic cells. Acts by binding to its coreceptor, GFRA2, leading to autophosphorylation and activation of the RET receptor. Heparan sulfate-binding is required for signaling. |
| Protein Name | Neurturin |
| Database Links | Reactome: R-HSA-419037Reactome: R-HSA-5673001Reactome: R-HSA-8853659 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Neurturin antibodyAnti-NRTN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
