Anti-Neuroserpin antibody (C-Term) (STJ70678)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Neuroserpin (C-Term) is suitable for use in ELISA, Western Blot, Immunohistochemistry and Flow Cytometry research applications. |
| Applications | Pep-ELISA/WB/IHC/FC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 48kDa band observed in lysates of cell lines Kelly and K562 and in Human Placenta and Mouse and Rat Brain lysates (calculated MW of 46.4kDa according to Human NP_005016.1, Mouse |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SERPINI1 |
| Gene ID | 5274 |
| Uniprot ID | NEUS_HUMAN |
| Accession Number | NP_005016.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | TMNTSGHDFEEL |
| Specificity | Reported variants represent identical protein (NP_005016.1; NP_001116224.1). |
Additional Info
| Function | Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator (Probable). |
| Protein Name | NeuroserpinPeptidase Inhibitor 12Pi-12Serpin I1 |
| Cellular Localisation | SecretedCytoplasmic VesicleSecretory Vesicle LumenPerikaryon |
| Alternative Antibody Names | Anti-Neuroserpin antibodyAnti-Peptidase Inhibitor 12 antibodyAnti-Pi-12 antibodyAnti-Serpin I1 antibodyAnti-SERPINI1 antibodyAnti-PI12 antibody |
Information sourced from Uniprot.org