Anti-Neuronal nuclei antigen/RNA binding protein fox-1 homolog 3 antibody (KLH) (STJA0040999)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antibody has been made against a peptide corresponding to N-terminal sequence (amino acids 5-24) of human FOX3 coupled to keyhole limpet hemocyanin (KLH).
General Information
| Short Description | Rabbit polyclonal anti-Neuronal nuclei antigen/RNA binding protein fox-1 homolog 3 (KLH) for use in IF, ICC, IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/ICC/IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity-purified |
| Dilution Range | WB 1:500-1:1000IHC 1:5000-1:10000ICC 1:5000-1:10000 |
| Formulation | Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide |
| Storage Instruction | Spin vial briefly before opening. Reconstitute with 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8°C After reconstitution of lyophilized antibody, aliquot and store at-20°C for |
Target Information
| Gene Symbol | RBFOX3 |
| Gene ID | 146713 |
| Uniprot ID | RFOX3_HUMAN |
| Immunogen | The antibody has been made against a peptide corresponding to N-terminal sequence (amino acids 5-24) of human FOX3 coupled to keyhole limpet hemocyanin (KLH). |
| Immunogen Region | KLH |
| Immunogen Sequence | Human |
| Specificity | Species cross-reactivity includes human, rat, and mouse. |
Additional Info
| Function | Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD). |
| Protein Name | Rna Binding Protein Fox-1 Homolog 3Fox-1 Homolog CNeuronal Nuclei AntigenNeun Antigen |
| Database Links | Reactome: R-HSA-9768919 |
| Cellular Localisation | NucleusCytoplasmLargely Restricted To Neuronal NucleiHoweverSignificant Cytoplasmic Localization In Neurons From Brains From Hiv-Infected Individuals With Cognitive Impairment |
| Alternative Antibody Names | Anti-Rna Binding Protein Fox-1 Homolog 3 antibodyAnti-Fox-1 Homolog C antibodyAnti-Neuronal Nuclei Antigen antibodyAnti-Neun Antigen antibodyAnti-RBFOX3 antibody |
Information sourced from Uniprot.org