Anti-Neuron specific enolase antibody (STJA0040901)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeMixed
ImmunogenRecombinant human Neuron Specific Enolase (NSE) expressed in and purified from E.coli
General Information
| Short Description | Rabbit polyclonal anti-Neuron specific enolase for use in ICC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ICC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | Mixed |
| Conjugation | Unconjugated |
| Purification | Whole serum |
| Dilution Range | WB 1:1000-1:2000IHC 0.3888888888888889 |
| Formulation | Lyophilized with sodium azide. |
| Storage Instruction | Spin vial briefly before opening. Reconstitute with 50 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution of lyophilized antibody, aliquot and store at-20°C for a higher stability. Avoid freeze-tha |
Target Information
| Gene Symbol | ENO2 |
| Gene ID | 2026 |
| Uniprot ID | ENOG_HUMAN |
| Immunogen | Recombinant human Neuron Specific Enolase (NSE) expressed in and purified from E.coli |
| Immunogen Sequence | Human |
| Specificity | Specifically recognizes ~47 kDa NSE protein in WB. Human and rat. Predicted to react with other mammals due to sequence homology. |
Additional Info
| Tissue Specificity | The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. |
| Function | Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival. |
| Protein Name | Gamma-Enolase2-Phospho-D-Glycerate Hydro-LyaseEnolase 2Neural EnolaseNeuron-Specific EnolaseNse |
| Database Links | Reactome: R-HSA-70171Reactome: R-HSA-70263 |
| Cellular Localisation | CytoplasmCell MembraneCan Translocate To The Plasma Membrane In Either The Homodimeric (Alpha/Alpha) Or Heterodimeric (Alpha/Gamma) Form |
| Alternative Antibody Names | Anti-Gamma-Enolase antibodyAnti-2-Phospho-D-Glycerate Hydro-Lyase antibodyAnti-Enolase 2 antibodyAnti-Neural Enolase antibodyAnti-Neuron-Specific Enolase antibodyAnti-Nse antibodyAnti-ENO2 antibody |
Information sourced from Uniprot.org