| Short Description : | Rabbit polyclonal anti-Neuron specific enolase for use in ICC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ICC/WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | Mixed |
| Conjugation: | Unconjugated |
| Purification: | Whole serum |
| Dilution Range: | WB 1:1000-1:2000IHC 0.3888888888888889 |
| Formulation: | Lyophilized with sodium azide. |
| Storage Instruction: | Spin vial briefly before opening. Reconstitute with 50 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution of lyophilized antibody, aliquot and store at-20°C for a higher stability. Avoid freeze-tha |
| Gene Symbol: | ENO2 |
| Gene ID: | 2026 |
| Uniprot ID: | ENOG_HUMAN |
| Immunogen: | Recombinant human Neuron Specific Enolase (NSE) expressed in and purified from E.coli |
| Immunogen Sequence: | Human |
| Specificity: | Specifically recognizes ~47 kDa NSE protein in WB. Human and rat. Predicted to react with other mammals due to sequence homology. |
| Tissue Specificity | The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. |
| Function | Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival. |
| Protein Name | Gamma-Enolase2-Phospho-D-Glycerate Hydro-LyaseEnolase 2Neural EnolaseNeuron-Specific EnolaseNse |
| Database Links | Reactome: R-HSA-70171Reactome: R-HSA-70263 |
| Cellular Localisation | CytoplasmCell MembraneCan Translocate To The Plasma Membrane In Either The Homodimeric (Alpha/Alpha) Or Heterodimeric (Alpha/Gamma) Form |
| Alternative Antibody Names | Anti-Gamma-Enolase antibodyAnti-2-Phospho-D-Glycerate Hydro-Lyase antibodyAnti-Enolase 2 antibodyAnti-Neural Enolase antibodyAnti-Neuron-Specific Enolase antibodyAnti-Nse antibodyAnti-ENO2 antibody |
Information sourced from Uniprot.org
