Anti-Neurocan antibody [R06-7R7] (STJA0037371)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Neurocan
General Information
| Short Description | Rabbit monoclonal anti-Neurocan for use in WB, IHC-P and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-7R7 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IP 1:50 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | NCAN |
| Gene ID | 1463 |
| Uniprot ID | NCAN_HUMAN |
| Immunogen | A synthesized peptide derived from human Neurocan |
Additional Info
| Tissue Specificity | Detected in cerebrospinal fluid (at protein level). Brain. |
| Post Translational Modifications | O-glycosylated.contains chondroitin sulfate. |
| Function | May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan.binds to hyaluronic acid. |
| Protein Name | Neurocan Core ProteinChondroitin Sulfate Proteoglycan 3 |
| Database Links | Reactome: R-HSA-1971475Reactome: R-HSA-2022870Reactome: R-HSA-2022923Reactome: R-HSA-2024101Reactome: R-HSA-3000178Reactome: R-HSA-3560783Reactome: R-HSA-3560801Reactome: R-HSA-3595172Reactome: R-HSA-3595174Reactome: R-HSA-3595177Reactome: R-HSA-373760Reactome: R-HSA-419037Reactome: R-HSA-4420332 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Neurocan Core Protein antibodyAnti-Chondroitin Sulfate Proteoglycan 3 antibodyAnti-NCAN antibodyAnti-CSPG3 antibodyAnti-NEUR antibody |
Information sourced from Uniprot.org