Anti-Nestin antibody [IHC105] (STJA0042224)

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STJA0042224
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Host: Rabbit
Applications: IHC-p
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Nestin for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : IHC105
Conjugation: Unconjugated
Formulation: Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Storage Instruction: Store at 2-8°C for up to 1 year. Do not freeze.
Gene Symbol: NES
Gene ID: 10763
Uniprot ID: NEST_HUMAN
Specificity: Tested and validated on tonsil, glioma tissue.
Tissue Specificity CNS stem cells.
Post Translational Modifications Constitutively phosphorylated. This increases during mitosis when the cytoplasmic intermediate filament network is reorganized.
Function Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
Protein Name Nestin
Database Links
Cellular Localisation
Alternative Antibody Names Anti-Nestin antibody
Anti-NES antibody
Anti-Nbla00170 antibody

Information sourced from Uniprot.org

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