Anti-NEK4 antibody (200-280) (STJ94397)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from Nek4. at AA range: 200-280
General Information
| Short Description | Rabbit polyclonal anti-Serine/threonine-protein kinase Nek4 (200-280) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NEK4 |
| Gene ID | 6787 |
| Uniprot ID | NEK4_HUMAN |
| Immunogen | Synthesized peptide derived from Nek4. at AA range: 200-280 |
| Immunogen Region | 200-280 |
| Specificity | Nek4 Polyclonal Antibody detects endogenous levels of Nek4 protein. |
Additional Info
| Tissue Specificity | Highest expression in adult heart, followed by pancreas, skeletal muscle, brain, testis, retina, liver, kidney, lung and placenta. Present in most primary carcinomas. |
| Function | Protein kinase that seems to act exclusively upon threonine residues. Required for normal entry into proliferative arrest after a limited number of cell divisions, also called replicative senescence. Required for normal cell cycle arrest in response to double-stranded DNA damage. |
| Protein Name | Serine/Threonine-Protein Kinase Nek4Never In Mitosis A-Related Kinase 4Nima-Related Protein Kinase 4Serine/Threonine-Protein Kinase 2Serine/Threonine-Protein Kinase Nrk2 |
| Database Links | |
| Cellular Localisation | Cell ProjectionCiliumCytoplasm |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase Nek4 antibodyAnti-Never In Mitosis A-Related Kinase 4 antibodyAnti-Nima-Related Protein Kinase 4 antibodyAnti-Serine/Threonine-Protein Kinase 2 antibodyAnti-Serine/Threonine-Protein Kinase Nrk2 antibodyAnti-NEK4 antibodyAnti-STK2 antibody |
Information sourced from Uniprot.org