Anti-NEK3 antibody (STJ191975)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Serine/threonine-protein kinase Nek3 for use in WB and ELISA in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NEK3 |
| Gene ID | 4752 |
| Uniprot ID | NEK3_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | NEK3 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Phosphorylation at Thr-479 regulates its catalytic activity. |
| Function | Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2. |
| Protein Name | Serine/Threonine-Protein Kinase Nek3Hspk 36Never In Mitosis A-Related Kinase 3Nima-Related Protein Kinase 3 |
| Database Links | |
| Cellular Localisation | CytoplasmCell ProjectionAxon |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase Nek3 antibodyAnti-Hspk 36 antibodyAnti-Never In Mitosis A-Related Kinase 3 antibodyAnti-Nima-Related Protein Kinase 3 antibodyAnti-NEK3 antibody |
Information sourced from Uniprot.org