Anti-Nectin-2 antibody [502-57] (STJ16100216)
SPECIFICATIONS
ClonalityMonoclonal
HostRat
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Rat monoclonal anti-Nectin-2 for use in IHC-F, FC, ELISA, IP and WB in Mouse and Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-F/FC/ELISA/IP/WB |
| Host | Rat |
| Reactivity | Mouse/Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 502-57 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 100 Mu g/mL |
| Dilution Range | FC 1:50IHC 1:50ELISA 1:50WB 1:50IP 1:50 |
| Formulation | PBS with 0.1% BSA and 0.02% sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | NECTIN2 |
| Gene ID | 5819 |
| Uniprot ID | NECT2_HUMAN |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein. (Microbial infection) Acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV). |
| Protein Name | Nectin-2Herpes Virus Entry Mediator BHerpesvirus Entry Mediator BHvebNectin Cell Adhesion Molecule 2Poliovirus Receptor-Related Protein 2Cd Antigen Cd112 |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-418990Reactome: R-HSA-420597 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Nectin-2 antibodyAnti-Herpes Virus Entry Mediator B antibodyAnti-Herpesvirus Entry Mediator B antibodyAnti-Hveb antibodyAnti-Nectin Cell Adhesion Molecule 2 antibodyAnti-Poliovirus Receptor-Related Protein 2 antibodyAnti-Cd Antigen Cd112 antibodyAnti-NECTIN2 antibodyAnti-HVEB antibodyAnti-PRR2 antibodyAnti-PVRL2 antibody |
Information sourced from Uniprot.org