| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-N-terminal EF-hand calcium-binding protein 2 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NECAB2 |
| Gene ID: |
54550 |
| Uniprot ID: |
NECA2_HUMAN |
| Specificity: |
This antibody detects endogenous levels of NECAB2 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human NECAB2 |
| Function | May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5.for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation. |
| Protein Name | N-Terminal Ef-Hand Calcium-Binding Protein 2Ef-Hand Calcium-Binding Protein 2Neuronal Calcium-Binding Protein 2Synaptotagmin-Interacting Protein 2Stip-2 |
| Cellular Localisation | CytoplasmCell ProjectionDendriteAxonCell MembraneColocalizes With Adora2a And/Or Mglur5/Grm5 At The Plasma MembraneFound In Neuronal SomataDetected In The Cytoplasm Of Striatal NeuronsAt Postsynaptic SitesFilling Dendritic Shafts And SpinesAnd At Presynaptic SitesFilling Axon Terminals |
| Alternative Antibody Names | Anti-N-Terminal Ef-Hand Calcium-Binding Protein 2 antibodyAnti-Ef-Hand Calcium-Binding Protein 2 antibodyAnti-Neuronal Calcium-Binding Protein 2 antibodyAnti-Synaptotagmin-Interacting Protein 2 antibodyAnti-Stip-2 antibodyAnti-NECAB2 antibodyAnti-EFCBP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
