| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NDUFV1 |
| Gene ID: | 4723 |
| Uniprot ID: | NDUV1_HUMAN |
| Immunogen Region: | 1-250 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human NDUFV1 (NP_009034.2). |
| Immunogen Sequence: | MLATRRLLGWSLPARVSVRF SGDTTAPKKTSFGSLKDEDR IFTNLYGRHDWRLKGSLSRG DWYKTKEILLKGPDWILGEI KTSGLRGRGGAGFPTGLKWS FMNKPSDGRPKYLVVNADEG EPGTCKDREILRHDPHKLLE GCLVGGRAMGARAAYIYIRG EFYNEASNLQVAIREAYEAG LIGKNACGSGYDFDVFVVRG AGAYICGEETALIESIEGKQ GKPRLKPPFPADVGVFGCP |
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Part of the peripheral arm of the enzyme, where the electrons from NADH are accepted by flavin mononucleotide (FMN) and then passed along a chain of iron-sulfur clusters by electron tunnelling to the final acceptor ubiquinone. Contains FMN, which is the initial electron acceptor as well as one iron-sulfur cluster. |
| Protein Name | Nadh Dehydrogenase Ubiquinone Flavoprotein 1 - Mitochondrial Ndufv1 Complex I-51kd Ci-51kd Nadh Dehydrogenase Flavoprotein 1 Nadh-Ubiquinone Oxidoreductase 51 Kda Subunit |
| Database Links | Reactome: R-HSA-611105 Reactome: R-HSA-6799198 Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Inner Membrane Peripheral Membrane Protein Matrix Side |
| Alternative Antibody Names | Anti-Nadh Dehydrogenase Ubiquinone Flavoprotein 1 - Mitochondrial antibody Anti-Ndufv1 antibody Anti-Complex I-51kd antibody Anti-Ci-51kd antibody Anti-Nadh Dehydrogenase Flavoprotein 1 antibody Anti-Nadh-Ubiquinone Oxidoreductase 51 Kda Subunit antibody Anti-NDUFV1 antibody Anti-UQOR1 antibody |
Information sourced from Uniprot.org