Anti-NDUFS8 antibody (35-210) (STJ115001)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NDUFS8 (35-210) antibody for use in WB, IF, ICC and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NDUFS8 |
| Gene ID | 4728 |
| Uniprot ID | NDUS8_HUMAN |
| Immunogen Region | 35-210 |
| Immunogen Sequence | TYKYVNMQDPEMDMKSVTDR AARTLLWTELFRGLGMTLSY LFREPATINYPFEKGPLSPR FRGEHALRRYPSGEERCIAC KLCEAICPAQAITIEAEPRA DGSRRTTRYDIDMTKCIYCG FCQEACPVDAIVEGPNFEFS TETHEELLYNKEKLLNNGDK WEAEIAANIQADYLYR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 35-210 of human NDUFS8 (NP_002487.1). |
Additional Info
| Tissue Specificity | Expressed in all tissues with the highest level in heart and skeletal muscle and the lowest level in lung. |
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I. |
| Protein Name | Nadh Dehydrogenase Ubiquinone Iron-Sulfur Protein 8 - MitochondrialComplex I-23kdCi-23kdNadh-Ubiquinone Oxidoreductase 23 Kda SubunitTyky Subunit |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-6799198 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Nadh Dehydrogenase Ubiquinone Iron-Sulfur Protein 8 - Mitochondrial antibodyAnti-Complex I-23kd antibodyAnti-Ci-23kd antibodyAnti-Nadh-Ubiquinone Oxidoreductase 23 Kda Subunit antibodyAnti-Tyky Subunit antibodyAnti-NDUFS8 antibody |
Information sourced from Uniprot.org