Anti-NDUFS4 antibody (1-175) (STJ115480)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NDUFS4 (1-175) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NDUFS4 |
| Gene ID | 4724 |
| Uniprot ID | NDUS4_HUMAN |
| Immunogen Region | 1-175 |
| Immunogen Sequence | MAAVSMSVVLRQTLWRRRAV AVAALSVSRVPTRSLRTSTW RLAQDQTQDTQLITVDEKLD ITTLTGVPEEHIKTRKVRIF VPARNNMQSGVNNTKKWKME FDTRERWENPLMGWASTADP LSNMVLTFSTKEDAVSFAEK NGWSYDIEERKVPKPKSKSY GANFSWNKRTRVSTK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-175 of human NDUFS4 (NP_002486.1). |
Additional Info
| Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
| Protein Name | Nadh Dehydrogenase Ubiquinone Iron-Sulfur Protein 4 - MitochondrialComplex I-18 KdaCi-18 KdaComplex I-AqdqCi-AqdqNadh-Ubiquinone Oxidoreductase 18 Kda Subunit |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-6799198 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix SideThe Interaction With Bcap31 Mediates Mitochondria Localization |
| Alternative Antibody Names | Anti-Nadh Dehydrogenase Ubiquinone Iron-Sulfur Protein 4 - Mitochondrial antibodyAnti-Complex I-18 Kda antibodyAnti-Ci-18 Kda antibodyAnti-Complex I-Aqdq antibodyAnti-Ci-Aqdq antibodyAnti-Nadh-Ubiquinone Oxidoreductase 18 Kda Subunit antibodyAnti-NDUFS4 antibody |
Information sourced from Uniprot.org