Anti-NDUFS1 antibody (80-290 aa) (STJ11107121)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NDUFS1 (80-290 aa) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NDUFS1 |
| Gene ID | 4719 |
| Uniprot ID | NDUS1_HUMAN |
| Immunogen Region | 80-290 aa |
| Immunogen Sequence | VEIEKAPKVVAACAMPVMKG WNILTNSEKSKKAREGVMEF LLANHPLDCPICDQGGECDL QDQSMMFGNDRSRFLEGKRA VEDKNIGPLVKTIMTRCIQC TRCIRFASEIAGVDDLGTTG RGNDMQVGTYIEKMFMSELS GNIIDICPVGALTSKPYAFT ARPWETRKTESIDVMDAVGS NIVVSTRTGEVMRILPRMHE DINEEWISDKT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 80-290 of human NDUFS1 (NP_004997.4). |
Additional Info
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for catalysing the entry and efficient transfer of electrons within complex I. Plays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes. |
| Protein Name | Nadh-Ubiquinone Oxidoreductase 75 Kda Subunit - MitochondrialComplex I-75kdCi-75kd |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-6799198Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Nadh-Ubiquinone Oxidoreductase 75 Kda Subunit - Mitochondrial antibodyAnti-Complex I-75kd antibodyAnti-Ci-75kd antibodyAnti-NDUFS1 antibody |
Information sourced from Uniprot.org