Anti-NDUFB3 antibody (1-98) (STJ116590)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NDUFB3 (1-98) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NDUFB3 |
| Gene ID | 4709 |
| Uniprot ID | NDUB3_HUMAN |
| Immunogen Region | 1-98 |
| Immunogen Sequence | MAHEHGHEHGHHKMELPDYR QWKIEGTPLETIQKKLAAKG LRDPWGRNEAWRYMGGFAKS VSFSDVFFKGFKWGFAAFVV AVGAEYYLESLNKDKKHH |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-98 of human NDUFB3 (NP_002482.1). |
Additional Info
| Post Translational Modifications | Methylation at His residues by METTL9 enhances complex I-mediated mitochondrial respiration. |
| Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
| Protein Name | Nadh Dehydrogenase Ubiquinone 1 Beta Subcomplex Subunit 3Complex I-B12Ci-B12Nadh-Ubiquinone Oxidoreductase B12 Subunit |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-6799198 |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Nadh Dehydrogenase Ubiquinone 1 Beta Subcomplex Subunit 3 antibodyAnti-Complex I-B12 antibodyAnti-Ci-B12 antibodyAnti-Nadh-Ubiquinone Oxidoreductase B12 Subunit antibodyAnti-NDUFB3 antibody |
Information sourced from Uniprot.org