Anti-NDUFA10 antibody (36-300) (STJ112162)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NDUFA10 (36-300) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NDUFA10 |
| Gene ID | 4705 |
| Uniprot ID | NDUAA_HUMAN |
| Immunogen Region | 36-300 |
| Immunogen Sequence | LRYGMWHFLLGDKASKRLTE RSRVITVDGNICTGKGKLAK EIAEKLGFKHFPEAGIHYPD STTGDGKPLATDYNGNCSLE KFYDDPRSNDGNSYRLQSWL YSSRLLQYSDALEHLLTTGQ GVVLERSIFSDFVFLEAMYN QGFIRKQCVDHYNEVKSVTI CDYLPPHLVIYIDVPVPEVQ RRIQKKGDPHEMKITSAYLQ DIENAYKKTFLPEMSEKCEV LQYSAREAQDSKKVVEDIE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 36-300 of human NDUFA10 (NP_004535.1). |
Additional Info
| Post Translational Modifications | Phosphorylation at Ser-250 by PINK1 is required for the binding and/or reduction of the complex I substrate ubiquinone. |
| Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
| Protein Name | Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Subunit 10 - MitochondrialComplex I-42kdCi-42kdNadh-Ubiquinone Oxidoreductase 42 Kda Subunit |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-6799198 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Subunit 10 - Mitochondrial antibodyAnti-Complex I-42kd antibodyAnti-Ci-42kd antibodyAnti-Nadh-Ubiquinone Oxidoreductase 42 Kda Subunit antibodyAnti-NDUFA10 antibody |
Information sourced from Uniprot.org