Anti-NDRG2 antibody (N-Term) (STJ72526)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-NDRG2 (N-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 45kDa band observed in Human Brain (Temporal Cortex) , Mouse and Rat Brain lysates (calculated MW of 40.8kDa according to NP_963293.1). Recommended concentration: 0.1-0.3µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | NDRG2 |
| Gene ID | 57447 |
| Uniprot ID | NDRG2_HUMAN |
| Accession Number | NP_963293.1 |
| Immunogen Region | N-Term |
| Immunogen Sequence | KEAELAARILLDQGQ |
| Specificity | This antibody is expected to recognize reported isoform a (NP_963293.1) only. Reported variants represent identical protein: NP_963831.1, NP_963293.1, NP_963834.1, NP_963833.1. |
Additional Info
| Function | Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation. |
| Protein Name | Protein Ndrg2N-Myc Downstream-Regulated Gene 2 ProteinProtein Syld709613 |
| Cellular Localisation | CytoplasmPerinuclear RegionCell ProjectionGrowth ConeIn NeuronsSeems To Concentrate At Axonal Growth ConePerinuclear In Neurons |
| Alternative Antibody Names | Anti-Protein Ndrg2 antibodyAnti-N-Myc Downstream-Regulated Gene 2 Protein antibodyAnti-Protein Syld709613 antibodyAnti-NDRG2 antibodyAnti-KIAA1248 antibodyAnti-SYLD antibody |
Information sourced from Uniprot.org