Anti-NCS1 antibody [R35-9B-6] (STJA0035508)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human NCS1
General Information
| Short Description | Rabbit monoclonal anti-NCS1 for use in WB, IHC-P and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R35-9B-6 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:100-1:200FC 1:50 |
| Formulation | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | NCS1 |
| Gene ID | 23413 |
| Uniprot ID | NCS1_HUMAN |
| Immunogen | A synthesized peptide derived from human NCS1 |
Additional Info
| Function | Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin. Stimulates PI4KB kinase activity. Involved in long-term synaptic plasticity through its interaction with PICK1. May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel. |
| Protein Name | Neuronal Calcium Sensor 1Ncs-1Frequenin HomologFrequenin-Like ProteinFrequenin-Like Ubiquitous Protein |
| Database Links | |
| Cellular Localisation | Golgi ApparatusPostsynaptic DensityCytoplasmPerinuclear RegionCell MembranePeripheral Membrane ProteinMembraneLipid-AnchorAssociated With Golgi StacksPost-Synaptic Densities Of DendritesAnd In The Pre-Synaptic Nerve Terminal At Neuromuscular Junctions |
| Alternative Antibody Names | Anti-Neuronal Calcium Sensor 1 antibodyAnti-Ncs-1 antibodyAnti-Frequenin Homolog antibodyAnti-Frequenin-Like Protein antibodyAnti-Frequenin-Like Ubiquitous Protein antibodyAnti-NCS1 antibodyAnti-FLUP antibodyAnti-FREQ antibody |
Information sourced from Uniprot.org