Anti-NCS1 antibody (91-190) [S5MR] (STJ11102695)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal NCS1 (91-190) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S5MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NCS1 |
| Gene ID | 23413 |
| Uniprot ID | NCS1_HUMAN |
| Immunogen Region | 91-190 |
| Immunogen Sequence | VTSRGTLDEKLRWAFKLYDL DNDGYITRNEMLDIVDAIYQ MVGNTVELPEEENTPEKRVD RIFAMMDKNADGKLTLQEFQ EGSKADPSIVQALSLYDGLV |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 91-190 of human NCS1 (P62166). |
Additional Info
| Function | Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin. Stimulates PI4KB kinase activity. Involved in long-term synaptic plasticity through its interaction with PICK1. May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel. |
| Protein Name | Neuronal Calcium Sensor 1Ncs-1Frequenin HomologFrequenin-Like ProteinFrequenin-Like Ubiquitous Protein |
| Database Links | |
| Cellular Localisation | Golgi ApparatusPostsynaptic DensityCytoplasmPerinuclear RegionCell MembranePeripheral Membrane ProteinMembraneLipid-AnchorAssociated With Golgi StacksPost-Synaptic Densities Of DendritesAnd In The Pre-Synaptic Nerve Terminal At Neuromuscular Junctions |
| Alternative Antibody Names | Anti-Neuronal Calcium Sensor 1 antibodyAnti-Ncs-1 antibodyAnti-Frequenin Homolog antibodyAnti-Frequenin-Like Protein antibodyAnti-Frequenin-Like Ubiquitous Protein antibodyAnti-NCS1 antibodyAnti-FLUP antibodyAnti-FREQ antibody |
Information sourced from Uniprot.org