Anti-NCL nanobody [SAA1204] (STJN000166)

SKU:
STJN000166
£195.50 - £1,319.50
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Short Description :Alpaca monoclonal nanobody anti-Nucleolin is suitable for use in ELISA, Flow Cytometry, Immunofluorescence, SPR and Western Blot research applications.
Applications:ELISA/FC/IF/SPR/WB
Host:Alpaca
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :SAA1204
Isotype:VHH-8His-Cys-tag
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:Purified by Nickel column.
Formulation:0.01M PBS, pH 7.4.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol:NCL
Gene ID:4691
Uniprot ID:NUCL_HUMAN
Function Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
Protein Name Nucleolin
Protein C23
Database Links Reactome: R-HSA-6791226
Reactome: R-HSA-9820960
Cellular Localisation Nucleus
Nucleolus
Cytoplasm
Localized In Cytoplasmic Mrnp Granules Containing Untranslated Mrnas
Alternative Nanobody Names Anti-Nucleolin nanobody
Anti-Protein C23 nanobody
Anti-NCL nanobody

Information sourced from Uniprot.org