Anti-NCKIPSD antibody (STJ191401)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-NCK-interacting protein with SH3 domain for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NCKIPSD |
| Gene ID | 51517 |
| Uniprot ID | SPN90_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | SPN90 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo. In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42. May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis. |
| Protein Name | Nck-Interacting Protein With Sh3 Domain54 Kda Vaca-Interacting Protein54 Kda Vimentin-Interacting ProteinVip5490 Kda Sh3 Protein Interacting With NckAf3p21Dia-Interacting Protein 1Dip-1Diaphanous Protein-Interacting ProteinSh3 Adapter Protein Spin90Wasp-Interacting Sh3-Domain ProteinWishWiskott-Aldrich Syndrome Protein-Interacting Protein |
| Database Links | Reactome: R-HSA-2029482Reactome: R-HSA-5663213Reactome: R-HSA-9664422 |
| Cellular Localisation | NucleusColocalizes With Drf1 At Membrane RufflesAnd With Nck At Z-Disks In Mature Cardiac Myocytes |
| Alternative Antibody Names | Anti-Nck-Interacting Protein With Sh3 Domain antibodyAnti-54 Kda Vaca-Interacting Protein antibodyAnti-54 Kda Vimentin-Interacting Protein antibodyAnti-Vip54 antibodyAnti-90 Kda Sh3 Protein Interacting With Nck antibodyAnti-Af3p21 antibodyAnti-Dia-Interacting Protein 1 antibodyAnti-Dip-1 antibodyAnti-Diaphanous Protein-Interacting Protein antibodyAnti-Sh3 Adapter Protein Spin90 antibodyAnti-Wasp-Interacting Sh3-Domain Protein antibodyAnti-Wish antibodyAnti-Wiskott-Aldrich Syndrome Protein-Interacting Protein antibodyAnti-NCKIPSD antibodyAnti-AF3P21 antibodyAnti-SPIN90 antibody |
Information sourced from Uniprot.org