Anti-NCAM antibody [123C3] (STJ16100875)

Anti-NCAM antibody [123C3] (STJ16100875)

SKU:
STJ16100875-1
€571.88
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: IHC-P/IHC-F/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-CD56 is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality : Monoclonal
Clone ID : 123C3
Conjugation: Unconjugated
Isotype: IgG1
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Concentration: 100 ug/mL
Dilution Range: IF 1:50
IHC 1:50
Storage Instruction: Store at 2-8°C upon receipt.
Background The antibody recognizes a transmembrane glycoprotein of 140 and 180 kD which has been identified as NCAM (Neural Cell Adhesion Module). At the international Workshop on SCLC antibodies 123C3 has been categorized as cluster 1 antibody. All cells in small cell carcinomas and carcinoids of the lung are strongly positive for 123C3. A minority of cases of other major types of lung carcinoma are sometimes positive as well: however this positivity is generally weak and focal. Adenoid cystic carcinomas of bronchial glands are strongly positive. Neuroblastoma s and Wilms tumors are usually also staining strongly positive. In non-small lung cell carcinomas, 123C3 staining has been associated with more advanced stage and a decreased survival after surgery. Furthermore, this antibody can be used to support diagnosis of lymphoma or to detect residual disease for cases of CD56 positive T/NK-cell lymphoma in which the neoplastic lymphoid cells are small and show minimal atypia, especially in small biopsies.

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ16100339 Anti-NCAM antibody [123C3.D5] (STJ16100339) Mouse Monoclonal Human IHC-P
STJ180065 Anti-NCAM1 antibody [123C3.D5] (STJ180065) Mouse Monoclonal Human IHC-P
STJ16101712 Anti-NCAM antibody [CD564] (STJ16101712) Mouse Monoclonal Human IHC-P
STJ16100190 Anti-NCAM antibody [MEM-188] (STJ16100190) Mouse Monoclonal Non-Human Primates/Human FC/IP/IHC-P/ICC
STJA0016491 Anti-CD56/NCAM antibody [MY31] {EF700} (STJA0016491) Mouse Monoclonal Human FC
!