Anti-NBAS antibody (1880-1960 aa) (STJ191061)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 1880-1960
General Information
| Short Description | Rabbit polyclonal anti-NBAS subunit of NRZ tethering complex (1880-1960 aa) for use in IHC and IF in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC-P 1:50-300IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NBAS |
| Gene ID | 51594 |
| Uniprot ID | NBAS_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 1880-1960 |
| Immunogen Region | 1880-1960 aa |
| Specificity | NBAS Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Involved in Golgi-to-endoplasmic reticulum (ER) retrograde transport.the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER. Required for normal embryonic development. May play a role in the nonsense-mediated decay pathway of mRNAs containing premature stop codons. |
| Protein Name | Nbas Subunit Of Nrz Tethering ComplexNeuroblastoma-Amplified Gene ProteinNeuroblastoma-Amplified Sequence |
| Database Links | Reactome: R-HSA-6811434 |
| Cellular Localisation | CytoplasmEndoplasmic ReticulumEndoplasmic Reticulum MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Nbas Subunit Of Nrz Tethering Complex antibodyAnti-Neuroblastoma-Amplified Gene Protein antibodyAnti-Neuroblastoma-Amplified Sequence antibodyAnti-NBAS antibodyAnti-NAG antibody |
Information sourced from Uniprot.org