Anti-Nat8l-Mouse antibody (211-223) (STJ73610)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Nat8l-Mouse (211-223) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 45-48kDa band observed in Human Cerebellum and Mouse Brain lysates, and approx. 48-50kDa in Rat Brain lysates (calculated MW of 32.8kDa according to Human NP_848652.2 and 32.7kD |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | NAT8L |
| Gene ID | 339983 |
| Uniprot ID | NAT8L_HUMAN |
| Accession Number | NP_001001985.3 |
| Immunogen Region | 211-223 |
| Immunogen Sequence | SVDSRFRGKGIAK |
Additional Info
| Function | Catalyzes the synthesis of N-acetylaspartate acid (NAA) from L-aspartate and acetyl-CoA. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake. |
| Protein Name | N-Acetylaspartate SynthetaseNaa SynthetaseCamello-Like Protein 3N-Acetyltransferase 8-Like Protein |
| Database Links | Reactome: R-HSA-8963693 |
| Cellular Localisation | CytoplasmMicrosome MembraneSingle-Pass Membrane ProteinMitochondrion MembraneEndoplasmic Reticulum MembraneIts Enzymatic Activity Contribution Is Quantitatively Larger In Mitochondrial Compartment Than In Extramitochondrial Compartment |
| Alternative Antibody Names | Anti-N-Acetylaspartate Synthetase antibodyAnti-Naa Synthetase antibodyAnti-Camello-Like Protein 3 antibodyAnti-N-Acetyltransferase 8-Like Protein antibodyAnti-NAT8L antibodyAnti-CML3 antibody |
Information sourced from Uniprot.org