| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Nat8l-Mouse (211-223) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 45-48kDa band observed in Human Cerebellum and Mouse Brain lysates, and approx. 48-50kDa in Rat Brain lysates (calculated MW of 32.8kDa according to Human NP_848652.2 and 32.7kD |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | NAT8L |
| Gene ID: | 339983 |
| Uniprot ID: | NAT8L_HUMAN |
| Immunogen Region: | 211-223 |
| Accession Number: | NP_001001985.3 |
| Immunogen Sequence: | SVDSRFRGKGIAK |
| Function | Catalyzes the synthesis of N-acetylaspartate acid (NAA) from L-aspartate and acetyl-CoA. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake. |
| Protein Name | N-Acetylaspartate SynthetaseNaa SynthetaseCamello-Like Protein 3N-Acetyltransferase 8-Like Protein |
| Database Links | Reactome: R-HSA-8963693 |
| Cellular Localisation | CytoplasmMicrosome MembraneSingle-Pass Membrane ProteinMitochondrion MembraneEndoplasmic Reticulum MembraneIts Enzymatic Activity Contribution Is Quantitatively Larger In Mitochondrial Compartment Than In Extramitochondrial Compartment |
| Alternative Antibody Names | Anti-N-Acetylaspartate Synthetase antibodyAnti-Naa Synthetase antibodyAnti-Camello-Like Protein 3 antibodyAnti-N-Acetyltransferase 8-Like Protein antibodyAnti-NAT8L antibodyAnti-CML3 antibody |
Information sourced from Uniprot.org