Anti-CCDC124 antibody (1-223) (STJ116646)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CCDC124 (1-223) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCDC124 |
| Gene ID | 115098 |
| Uniprot ID | CC124_HUMAN |
| Immunogen Region | 1-223 |
| Immunogen Sequence | MPKKFQGENTKSAAARARRA EAKAAADAKKQKELEDAYWK DDDKHVMRKEQRKEEKEKRR LDQLERKKETQRLLEEEDSK LKGGKAPRVATSSKVTRAQI EDTLRRDHQLREAPDTAEKA KSHLEVPLEENVNRRVLEEG SVEARTIEDAIAVLSVAEEA ADRHPERRMRAAFTAFEEAQ LPRLKQENPNMRLSQLKQLL KKEWLRSPDNPMNQRAVPFN APK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-223 of human CCDC124 (NP_612451.1). |
Additional Info
| Tissue Specificity | Ubiquitously expressed. |
| Function | Ribosome-binding protein involved in ribosome hibernation: associates with translationally inactive ribosomes and stabilizes the nonrotated conformation of the 80S ribosome, thereby promoting ribosome preservation and storage. Also required for proper progression of late cytokinetic stages. |
| Protein Name | Coiled-Coil Domain-Containing Protein 124 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeMidbodyColocalizes With Gamma-Tubulin At InterphaseProphaseMetaphaseAnd AnaphaseRelocates From Centrosome To Midbody At Telophase |
| Alternative Antibody Names | Anti-Coiled-Coil Domain-Containing Protein 124 antibodyAnti-CCDC124 antibody |
Information sourced from Uniprot.org