Anti-NAT8L antibody (218-268 aa) (STJ195129)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human NAT8L at the amino acid range 218-268
General Information
| Short Description | Rabbit polyclonal anti-N-acetylaspartate synthetase (218-268 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NAT8L |
| Gene ID | 339983 |
| Uniprot ID | NAT8L_HUMAN |
| Immunogen | Synthesized peptide derived from the human NAT8L at the amino acid range 218-268 |
| Immunogen Region | 218-268 aa |
| Specificity | This antibody detects endogenous levels of NAT8L at Human/Mouse/Rat |
Additional Info
| Function | Catalyzes the synthesis of N-acetylaspartate acid (NAA) from L-aspartate and acetyl-CoA. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake. |
| Protein Name | N-Acetylaspartate SynthetaseNaa SynthetaseCamello-Like Protein 3N-Acetyltransferase 8-Like Protein |
| Database Links | Reactome: R-HSA-8963693 |
| Cellular Localisation | CytoplasmMicrosome MembraneSingle-Pass Membrane ProteinMitochondrion MembraneEndoplasmic Reticulum MembraneIts Enzymatic Activity Contribution Is Quantitatively Larger In Mitochondrial Compartment Than In Extramitochondrial Compartment |
| Alternative Antibody Names | Anti-N-Acetylaspartate Synthetase antibodyAnti-Naa Synthetase antibodyAnti-Camello-Like Protein 3 antibodyAnti-N-Acetyltransferase 8-Like Protein antibodyAnti-NAT8L antibodyAnti-CML3 antibody |
Information sourced from Uniprot.org