Anti-NANS antibody (STJA0009596)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human NANS
General Information
| Short Description | Rabbit polyclonal anti-Sialic acid synthase for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NANS |
| Gene ID | 54187 |
| Uniprot ID | SIAS_HUMAN |
| Immunogen | Synthesized peptide derived from human NANS |
| Specificity | This antibody detects endogenous levels of NANS at Human |
Additional Info
| Function | Catalyzes the condensation of phosphoenolpyruvate (PEP) and N-acetylmannosamine 6-phosphate (ManNAc-6-P) to synthesize N-acetylneuraminate-9-phosphate (Neu5Ac-9-P). Also catalyzes the condensation of PEP and D-mannose 6-phosphate (Man-6-P) to produce 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate 9-phosphate (KDN-9-P). Neu5Ac-9-P and KDN-9-P are the phosphorylated forms of sialic acids N-acetylneuraminic acid (Neu5Ac) and deaminoneuraminic acid (KDN), respectively. Required for brain and skeletal development. |
| Protein Name | N-Acetylneuraminate-9-Phosphate Synthase3-Deoxy-D-Glycero-D-Galacto-Nononate 9-Phosphate SynthaseN-Acetylneuraminic Acid Phosphate SynthaseNansSialic Acid Phosphate SynthaseSialic Acid Synthase |
| Database Links | Reactome: R-HSA-4085001 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-N-Acetylneuraminate-9-Phosphate Synthase antibodyAnti-3-Deoxy-D-Glycero-D-Galacto-Nononate 9-Phosphate Synthase antibodyAnti-N-Acetylneuraminic Acid Phosphate Synthase antibodyAnti-Nans antibodyAnti-Sialic Acid Phosphate Synthase antibodyAnti-Sialic Acid Synthase antibodyAnti-NANS antibodyAnti-SAS antibody |
Information sourced from Uniprot.org