Anti-NANS antibody (1-359aa) [AT1G6] (STJA0041612)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenRecombinant human NANS (1-359aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-NANS (1-359aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT1G6 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-G affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NANS |
| Gene ID | 54187 |
| Uniprot ID | SIAS_HUMAN |
| Accession Number | NP_061819 |
| Immunogen | Recombinant human NANS (1-359aa) purified from E. coli |
| Immunogen Region | 1-359aa |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | Catalyzes the condensation of phosphoenolpyruvate (PEP) and N-acetylmannosamine 6-phosphate (ManNAc-6-P) to synthesize N-acetylneuraminate-9-phosphate (Neu5Ac-9-P). Also catalyzes the condensation of PEP and D-mannose 6-phosphate (Man-6-P) to produce 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate 9-phosphate (KDN-9-P). Neu5Ac-9-P and KDN-9-P are the phosphorylated forms of sialic acids N-acetylneuraminic acid (Neu5Ac) and deaminoneuraminic acid (KDN), respectively. Required for brain and skeletal development. |
| Protein Name | N-Acetylneuraminate-9-Phosphate Synthase3-Deoxy-D-Glycero-D-Galacto-Nononate 9-Phosphate SynthaseN-Acetylneuraminic Acid Phosphate SynthaseNansSialic Acid Phosphate SynthaseSialic Acid Synthase |
| Database Links | Reactome: R-HSA-4085001 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-N-Acetylneuraminate-9-Phosphate Synthase antibodyAnti-3-Deoxy-D-Glycero-D-Galacto-Nononate 9-Phosphate Synthase antibodyAnti-N-Acetylneuraminic Acid Phosphate Synthase antibodyAnti-Nans antibodyAnti-Sialic Acid Phosphate Synthase antibodyAnti-Sialic Acid Synthase antibodyAnti-NANS antibodyAnti-SAS antibody |
Information sourced from Uniprot.org