Host: |
Rabbit |
Applications: |
WB/ELISA/IHC |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Nanos homolog 1 (151-200 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
NANOS1 |
Gene ID: |
340719 |
Uniprot ID: |
NANO1_HUMAN |
Immunogen Region: |
151-200 aa |
Specificity: |
Nanos Homologue 1 (NANOS1) Polyclonal Antibody detects endogenous levels of Nanos Homologue 1 (NANOS1) |
Immunogen: |
Synthesized peptide derived from Nanos Homologue 1 (NANOS1) at the amino acid range 151-200 |
Function | May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion. |
Protein Name | Nanos Homolog 1Nos-1Ec_rep1a |
Cellular Localisation | CytoplasmPerinuclear RegionColocalizes With Snapin And Pum2 In The Perinuclear Region Of Germ Cells |
Alternative Antibody Names | Anti-Nanos Homolog 1 antibodyAnti-Nos-1 antibodyAnti-Ec_rep1a antibodyAnti-NANOS1 antibodyAnti-NOS1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance