• HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human NLRP2 with DYKDDDDK tag probed with STJ72170 (1ug/ml) in Lane A and probed with anti-DYKDDDDK Tag (1/1000) in lane C. Mock-transfected HEK293 probed with STJ72170 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence.

Anti-NALP2/NLRP antibody (C-Term) (STJ72170)

SKU:
STJ72170-100

£303.50
Shipping:
Free Shipping
Current Stock:
Host: Goat
Applications: Pep-ELISA/WB-Trf
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-NALP2/NLRP (C-Term) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: ELISA-antibody detection limit dilution 1:4000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: NLRP2
Gene ID: 55655
Uniprot ID: NALP2_HUMAN
Immunogen Region: C-Term
Accession Number: NP_060322.1
Immunogen Sequence: TEKHHPWAERPSSHD
Function Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature pro-inflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of pro-inflammatory caspases.
Protein Name Nacht - Lrr And Pyd Domains-Containing Protein 2
Nucleotide-Binding Site Protein 1
Pyrin Domain And Nacht Domain-Containing Protein 1
Pyrin-Containing Apaf1-Like Protein 2
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Nacht - Lrr And Pyd Domains-Containing Protein 2 antibody
Anti-Nucleotide-Binding Site Protein 1 antibody
Anti-Pyrin Domain And Nacht Domain-Containing Protein 1 antibody
Anti-Pyrin-Containing Apaf1-Like Protein 2 antibody
Anti-NLRP2 antibody
Anti-NALP2 antibody
Anti-NBS1 antibody
Anti-PAN1 antibody
Anti-PYPAF2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance