| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NAF1 (150-400) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NAF1 |
| Gene ID: |
92345 |
| Uniprot ID: |
NAF1_HUMAN |
| Immunogen Region: |
150-400 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 150-400 of human NAF1 (NP_612395.2). |
| Immunogen Sequence: |
PPVLSDGDDDLQIEKENKNF PLKTKDELLLNELPSVEELT IILPEDIELKPLGMVSSIIE QLVIIESMTNLPPVNEETVI FKSDRQAAGKIFEIFGPVAH PFYVLRFNSSDHIESKGIKI KETMYFAPSMKDFTQYIFTE KLKQDKGSDASWKNDQEPPP EALDFSDDEKEKEAKQRKKS QIQGRKKLKSEFNEPGEDFT EVHQNWNAHSSASEHAKGYR NREFTRGFSRARYPRSCHG |
| Function | RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4. |
| Protein Name | H/Aca Ribonucleoprotein Complex Non-Core Subunit Naf1Hnaf1 |
| Cellular Localisation | CytoplasmNucleusShuttles Between The Cytoplasm And The NucleusAbsent From The Nucleolus |
| Alternative Antibody Names | Anti-H/Aca Ribonucleoprotein Complex Non-Core Subunit Naf1 antibodyAnti-Hnaf1 antibodyAnti-NAF1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
