| Short Description : | Rabbit polyclonal anti-NAC-alpha domain-containing protein 1 (376-425) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000IHC-p 1:50-300 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NACAD |
| Gene ID: | 23148 |
| Uniprot ID: | NACAD_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NACAD. AA range:376-425 |
| Immunogen Region: | 376-425 |
| Specificity: | NACAD Polyclonal Antibody detects endogenous levels of NACAD protein. |
| Function | May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). |
| Protein Name | Nac-Alpha Domain-Containing Protein 1 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Nac-Alpha Domain-Containing Protein 1 antibodyAnti-NACAD antibodyAnti-KIAA0363 antibody |
Information sourced from Uniprot.org
