Anti-NACA2 antibody (58-108 aa) (STJ197852)

SKU:
STJ197852
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Nascent polypeptide-associated complex subunit alpha-2 (58-108 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Rat/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:1000-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:NACA2
Gene ID:342538
Uniprot ID:NACA2_HUMAN
Immunogen:Synthesized peptide derived from the human NACA2 at the amino acid range 58-108
Immunogen Region:58-108 aa
Specificity:This antibody detects endogenous levels of human NACA2
Function Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).
Protein Name Nascent Polypeptide-Associated Complex Subunit Alpha-2
Alpha-Nac-Like
Hom S 2.01
Nascent Polypeptide-Associated Complex Subunit Alpha-Like
Nac-Alpha-Like
Database Links
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Nascent Polypeptide-Associated Complex Subunit Alpha-2 antibody
Anti-Alpha-Nac-Like antibody
Anti-Hom S 2.01 antibody
Anti-Nascent Polypeptide-Associated Complex Subunit Alpha-Like antibody
Anti-Nac-Alpha-Like antibody
Anti-NACA2 antibody
Anti-NACAL antibody

Information sourced from Uniprot.org