Anti-NAB2 antibody (261-310) (STJ94340)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human NAB2. AA range:261-310
General Information
| Short Description | Rabbit polyclonal anti-NGFI-A-binding protein 2 (261-310) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NAB2 |
| Gene ID | 4665 |
| Uniprot ID | NAB2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NAB2. AA range:261-310 |
| Immunogen Region | 261-310 |
| Specificity | NAB2 Polyclonal Antibody detects endogenous levels of NAB2 protein. |
Additional Info
| Tissue Specificity | Widely expressed at low levels. Highly expressed in melanoma cell lines. |
| Post Translational Modifications | Sumoylation by EGR2 represses EGR2 transcriptional activity in hindbrain. |
| Function | Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability. |
| Protein Name | Ngfi-A-Binding Protein 2Egr-1-Binding Protein 2Melanoma-Associated Delayed Early Response ProteinProtein Mader |
| Database Links | Reactome: R-HSA-9031628Reactome: R-HSA-9619665 |
| Cellular Localisation | NucleusIsoform 2 Is Not Localized To The Nucleus |
| Alternative Antibody Names | Anti-Ngfi-A-Binding Protein 2 antibodyAnti-Egr-1-Binding Protein 2 antibodyAnti-Melanoma-Associated Delayed Early Response Protein antibodyAnti-Protein Mader antibodyAnti-NAB2 antibodyAnti-MADER antibody |
Information sourced from Uniprot.org