Anti-MZT2B antibody (1-158) (STJ112025)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MZT2B (1-158) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MZT2B |
| Gene ID | 80097 |
| Uniprot ID | MZT2B_HUMAN |
| Immunogen Region | 1-158 |
| Immunogen Sequence | MAAQGVGPGPGSAAPPGLEA ARQKLALRRKKVLSTEEMEL YELAQAAGGAIDPDVFKILV DLLKLNVAPLAVFQMLKSMC AGQRLASEPQDPAAVSLPTS SVPETRGRNKGSAALGGALA LAERSSREGSSQRMPRQPSA TRLPKGGGPGKSPTRGST |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-158 of human MZT2B (NP_079305.2). |
Additional Info
| Function | Required for the recruitment and the assembly of the gamma-tubulin ring complex (gTuRC) at the centrosome. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation. |
| Protein Name | Mitotic-Spindle Organizing Protein 2bMitotic-Spindle Organizing Protein Associated With A Ring Of Gamma-Tubulin 2b |
| Database Links | Reactome: R-HSA-380270Reactome: R-HSA-380320 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindle |
| Alternative Antibody Names | Anti-Mitotic-Spindle Organizing Protein 2b antibodyAnti-Mitotic-Spindle Organizing Protein Associated With A Ring Of Gamma-Tubulin 2b antibodyAnti-MZT2B antibodyAnti-FAM128B antibodyAnti-MOZART2B antibody |
Information sourced from Uniprot.org