Anti-MYZAP antibody (STJA0008666)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human GCOM1
General Information
| Short Description | Rabbit polyclonal anti-Myocardial zonula adherens protein for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYZAP |
| Gene ID | 100820829/145781 |
| Uniprot ID | MYZAP_HUMAN |
| Immunogen | Synthesized peptide derived from human GCOM1 |
| Specificity | This antibody detects endogenous levels of GCOM1 at Human, Mouse, Rat |
Additional Info
| Function | Plays a role in cellular signaling via Rho-related GTP-binding proteins and subsequent activation of transcription factor SRF. Targets TJP1 to cell junctions. In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1. |
| Protein Name | Myocardial Zonula Adherens ProteinGrinl1a Upstream ProteinGup |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell MembranePeripheral Membrane ProteinCytoplasmic SideMyofibrilSarcomereI BandZ LineCell JunctionDetected Predominantly At The Intercalated Disk In CardiomyocytesAnd At Low Levels On Sarcomeric Z DisksColocalizes With F-ActinColocalizes With Cortical Actin |
| Alternative Antibody Names | Anti-Myocardial Zonula Adherens Protein antibodyAnti-Grinl1a Upstream Protein antibodyAnti-Gup antibodyAnti-MYZAP antibodyAnti-MYOZAP antibody |
Information sourced from Uniprot.org