| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-MYRIP/SLAC2C (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.3-1µg/mlIHC-3.75µg/mlELISA-antibody detection limit dilution 1:64000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
MYRIP |
| Gene ID: |
25924 |
| Uniprot ID: |
MYRIP_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_056275.2 |
| Immunogen Sequence: |
KDLMEPALESAVMY |
| Function | Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release. |
| Protein Name | Rab Effector MyripExophilin-8Myosin-Viia- And Rab-Interacting ProteinSynaptotagmin-Like Protein Lacking C2 Domains CSlac2-CSlp Homolog Lacking C2 Domains C |
| Database Links | Reactome: R-HSA-264876 |
| Cellular Localisation | CytoplasmPerinuclear RegionCytoplasmic VesicleSecretory VesicleIn Presynaptic And Postsynaptic Areas In Photoreceptor Cells And In The Basal Microvilli Of Retinal Pigment Epithelium CellsAssociated With MelanosomesColocalizes With Actin Filaments |
| Alternative Antibody Names | Anti-Rab Effector Myrip antibodyAnti-Exophilin-8 antibodyAnti-Myosin-Viia- And Rab-Interacting Protein antibodyAnti-Synaptotagmin-Like Protein Lacking C2 Domains C antibodyAnti-Slac2-C antibodyAnti-Slp Homolog Lacking C2 Domains C antibodyAnti-MYRIP antibodyAnti-SLAC2C antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
