Anti-MYRIP antibody (591-641) (STJA0006483)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MYRIP AA range: 591-641
General Information
| Short Description | Rabbit polyclonal anti-Rab effector MyRIP (591-641) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYRIP |
| Gene ID | 25924 |
| Uniprot ID | MYRIP_HUMAN |
| Immunogen | Synthesized peptide derived from human MYRIP AA range: 591-641 |
| Immunogen Region | 591-641 |
| Specificity | This antibody detects endogenous levels of human MYRIP |
Additional Info
| Function | Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release. |
| Protein Name | Rab Effector MyripExophilin-8Myosin-Viia- And Rab-Interacting ProteinSynaptotagmin-Like Protein Lacking C2 Domains CSlac2-CSlp Homolog Lacking C2 Domains C |
| Database Links | Reactome: R-HSA-264876Reactome: R-HSA-9824585 |
| Cellular Localisation | CytoplasmPerinuclear RegionCytoplasmic VesicleSecretory VesicleIn Presynaptic And Postsynaptic Areas In Photoreceptor Cells And In The Basal Microvilli Of Retinal Pigment Epithelium CellsAssociated With MelanosomesColocalizes With Actin Filaments |
| Alternative Antibody Names | Anti-Rab Effector Myrip antibodyAnti-Exophilin-8 antibodyAnti-Myosin-Viia- And Rab-Interacting Protein antibodyAnti-Synaptotagmin-Like Protein Lacking C2 Domains C antibodyAnti-Slac2-C antibodyAnti-Slp Homolog Lacking C2 Domains C antibodyAnti-MYRIP antibodyAnti-SLAC2C antibody |
Information sourced from Uniprot.org