| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MYOZ2 (1-264) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MYOZ2 |
| Gene ID: |
51778 |
| Uniprot ID: |
MYOZ2_HUMAN |
| Immunogen Region: |
1-264 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human MYOZ2 (NP_057683.1). |
| Immunogen Sequence: |
MLSHNTMMKQRKQQATAIMK EVHGNDVDGMDLGKKVSIPR DIMLEELSHLSNRGARLFKM RQRRSDKYTFENFQYQSRAQ INHSIAMQNGKVDGSNLEGG SQQAPLTPPNTPDPRSPPNP DNIAPGYSGPLKEIPPEKFN TTAVPKYYQSPWEQAISNDP ELLEALYPKLFKPEGKAELP DYRSFNRVATPFGGFEKASR MVKFKVPDFELLLLTDPRFM SFVNPLSGRRSFNRTPKGW |
| Tissue Specificity | Expressed specifically in heart and skeletal muscle. |
| Function | Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis. |
| Protein Name | Myozenin-2Calsarcin-1Fatz-Related Protein 2 |
| Cellular Localisation | CytoplasmMyofibrilSarcomereZ LineColocalizes With Actn1 And Ppp3ca At The Z-Line Of Heart And Skeletal Muscle |
| Alternative Antibody Names | Anti-Myozenin-2 antibodyAnti-Calsarcin-1 antibodyAnti-Fatz-Related Protein 2 antibodyAnti-MYOZ2 antibodyAnti-C4orf5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
