Anti-MYOT antibody (259-314) (STJ28522)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MYOT (259-314) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:10-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYOT |
| Gene ID | 9499 |
| Uniprot ID | MYOTI_HUMAN |
| Immunogen Region | 259-314 |
| Immunogen Sequence | RPNQTLPAPKQLRVRPTFSK YLALNGKGLNVKQAFNPEGE FQRLAAQSGLYESEEL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 259-314 of human MYOT (NP_001129412.1). |
Additional Info
| Tissue Specificity | Expressed in skeletal muscle (at protein level). Expressed in skeletal muscle, heart, bone marrow and thyroid gland. |
| Function | Component of a complex of multiple actin cross-linking proteins. Involved in the control of myofibril assembly and stability at the Z lines in muscle cells. |
| Protein Name | Myotilin57 Kda Cytoskeletal ProteinMyofibrillar Titin-Like Ig Domains ProteinTitin Immunoglobulin Domain Protein |
| Database Links | |
| Cellular Localisation | Cell MembraneSarcolemmaCytoplasmCytoskeletonMyofibrilSarcomereZ LineSarcomericAlso Localized To The SarcolemmaColocalizes With Myoz1 At The Z-Lines In Skeletal Muscle |
| Alternative Antibody Names | Anti-Myotilin antibodyAnti-57 Kda Cytoskeletal Protein antibodyAnti-Myofibrillar Titin-Like Ig Domains Protein antibodyAnti-Titin Immunoglobulin Domain Protein antibodyAnti-MYOT antibodyAnti-TTID antibody |
Information sourced from Uniprot.org