Anti-MYOD1 antibody (280-330) {Biotin} (STJ501859)

SKU:
STJ501859-100

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Host: Rabbit
Applications: ELISA/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MYOD1 (280-330) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.58 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: MYOD1
Gene ID: 4654
Uniprot ID: MYOD1_HUMAN
Immunogen Region: 280-330
Immunogen: Synthetic peptide taken within amino acid sequence 280-330 on human MyoD1 protein.
Post Translational Modifications Phosphorylated by CDK9. This phosphorylation promotes its function in muscle differentiation. Acetylated by a complex containing EP300 and PCAF. The acetylation is essential to activate target genes. Conversely, its deacetylation by SIRT1 inhibits its function. Ubiquitinated on the N-terminus.which is required for proteasomal degradation. Methylation at Lys-104 by EHMT2/G9a inhibits myogenic activity.
Function Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins.
Protein Name Myoblast Determination Protein 1
Class C Basic Helix-Loop-Helix Protein 1
Bhlhc1
Myogenic Factor 3
Myf-3
Database Links Reactome: R-HSA-525793
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Myoblast Determination Protein 1 antibody
Anti-Class C Basic Helix-Loop-Helix Protein 1 antibody
Anti-Bhlhc1 antibody
Anti-Myogenic Factor 3 antibody
Anti-Myf-3 antibody
Anti-MYOD1 antibody
Anti-BHLHC1 antibody
Anti-MYF3 antibody
Anti-MYOD antibody

Information sourced from Uniprot.org

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