Anti-MYO5A antibody (Internal) (STJ72335)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-MYO5A (Internal) is suitable for use in ELISA, Western Blot and Immunofluorescence research applications. |
| Applications | Pep-ELISA/WB/IF |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 200kDa band observed in lysates of cell line Jurkat (calculated MW of 215kDa according to NP_000250.3). Recommended concentration: 1-3µg/ml.IF: Transverse sections of Mouse |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | MYO5A |
| Gene ID | 4644 |
| Uniprot ID | MYO5A_HUMAN |
| Accession Number | NP_000250.3; NP_001135967.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | ETKQLELDLN |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_000250.3; NP_001135967.1). |
Additional Info
| Function | Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation. |
| Protein Name | Unconventional Myosin-VaDilute Myosin Heavy Chain - Non-MuscleMyosin Heavy Chain 12Myosin-12Myoxin |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-2029482Reactome: R-HSA-264876Reactome: R-HSA-9664422Reactome: R-HSA-9824585 |
| Alternative Antibody Names | Anti-Unconventional Myosin-Va antibodyAnti-Dilute Myosin Heavy Chain - Non-Muscle antibodyAnti-Myosin Heavy Chain 12 antibodyAnti-Myosin-12 antibodyAnti-Myoxin antibodyAnti-MYO5A antibodyAnti-MYH12 antibody |
Information sourced from Uniprot.org