Anti-MYO5A antibody (950-1150) (STJ111872)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MYO5A (950-1150) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYO5A |
| Gene ID | 4644 |
| Uniprot ID | MYO5A_HUMAN |
| Immunogen Region | 950-1150 |
| Immunogen Sequence | LTNLEGIYNSETEKLRSDLE RLQLSEEEAKVATGRVLSLQ EEIAKLRKDLEQTRSEKKCI EEHADRYKQETEQLVSNLKE ENTLLKQEKEALNHRIVQQA KEMTETMEKKLVEETKQLEL DLNDERLRYQNLLNEFSRLE ERYDDLKEEMTLMVHVPKPG HKRTDSTHSSNESEYIFSSE IAEMEDIPSRTEEPSEKKVP L |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 950-1150 of human MYO5A (NP_000250.3). |
Additional Info
| Tissue Specificity | Detected in melanocytes. |
| Function | Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Can hydrolyze ATP in the presence of actin, which is essential for its function as a motor protein. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation. |
| Protein Name | Unconventional Myosin-VaDilute Myosin Heavy Chain - Non-MuscleMyosin Heavy Chain 12Myosin-12Myoxin |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-2029482Reactome: R-HSA-264876Reactome: R-HSA-9664422Reactome: R-HSA-9824585 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Unconventional Myosin-Va antibodyAnti-Dilute Myosin Heavy Chain - Non-Muscle antibodyAnti-Myosin Heavy Chain 12 antibodyAnti-Myosin-12 antibodyAnti-Myoxin antibodyAnti-MYO5A antibodyAnti-MYH12 antibody |
Information sourced from Uniprot.org