Anti-MYO18B antibody (1680-1760 aa) (STJ191017)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 1680-1760
General Information
| Short Description | Rabbit polyclonal anti-Unconventional myosin-XVIIIb (1680-1760 aa) for use in IHC and IF in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC-P 1:50-300IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYO18B |
| Gene ID | 84700 |
| Uniprot ID | MY18B_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 1680-1760 |
| Immunogen Region | 1680-1760 aa |
| Specificity | MY18B Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression.restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth. |
| Protein Name | Unconventional Myosin-Xviiib |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusMyofibrilSarcomerePunctate Pattern In Undifferentiated MyoblastsNuclearOn Primary Cardiomyocytes And Adult MuscleA Partial Sarcomeric Location Was Found In Some Cardiomyocytes |
| Alternative Antibody Names | Anti-Unconventional Myosin-Xviiib antibodyAnti-MYO18B antibody |
Information sourced from Uniprot.org