| Host: |
Rabbit |
| Applications: |
WB/ELISA/IHC |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Unconventional myosin-XVI (1050-1130) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-p 1:50-300ELISA 2000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MYO16 |
| Gene ID: |
23026 |
| Uniprot ID: |
MYO16_HUMAN |
| Immunogen Region: |
1050-1130 |
| Specificity: |
Myosin XVI Polyclonal Antibody detects endogenous levels of Myosin XVI protein. |
| Immunogen: |
Synthesized peptide derived from Myosin XVI. at AA range: 1050-1130 |
| Post Translational Modifications | Phosphorylated on tyrosine residues by FYN upon stimulation with CNTN5. |
| Function | Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development. Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis. |
| Protein Name | Unconventional Myosin-XviNeuronal Tyrosine-Phosphorylated Phosphoinositide-3-Kinase Adapter 3Unconventional Myosin-16 |
| Cellular Localisation | CytoplasmFound In Puncta In Soma And Processes Of Astrocytes And Dissociated Cerebellar Cells With The Morphology Of Migrating Granule Cells |
| Alternative Antibody Names | Anti-Unconventional Myosin-Xvi antibodyAnti-Neuronal Tyrosine-Phosphorylated Phosphoinositide-3-Kinase Adapter 3 antibodyAnti-Unconventional Myosin-16 antibodyAnti-MYO16 antibodyAnti-KIAA0865 antibodyAnti-MYO16B antibodyAnti-NYAP3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
