Anti-MYLK3 antibody (100-200) (STJ28746)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MYLK3 (100-200) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYLK3 |
| Gene ID | 91807 |
| Uniprot ID | MYLK3_HUMAN |
| Immunogen Region | 100-200 |
| Immunogen Sequence | MQQDAAQHGARLEALFRMVA AVDRAIALVGATFQKSKVAD FLMQGRVPWRRGSPGDSPEE NKERVEEEGGKPKHVLSTSG VQSDAREPGEESQKADVLEG T |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human MYLK3 (NP_872299.2). |
Additional Info
| Tissue Specificity | Restricted to heart. |
| Post Translational Modifications | Phosphorylated on serine residues. |
| Function | Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility. |
| Protein Name | Myosin Light Chain Kinase 3Cardiac-Mybp-C-Associated Ca/Cam KinaseCardiac-Mlck |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Myosin Light Chain Kinase 3 antibodyAnti-Cardiac-Mybp-C-Associated Ca/Cam Kinase antibodyAnti-Cardiac-Mlck antibodyAnti-MYLK3 antibodyAnti-MLCK antibody |
Information sourced from Uniprot.org