Anti-MYH7/Beta-MHC antibody (1240-1340 aa) [SRM5160] (STJ11107004)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal MYH7/Beta-MHC (1240-1340 aa) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM5160 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:3000-1:12000IF/ICC:1:200-1:800ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
Target Information
| Gene Symbol | MYH7 |
| Gene ID | 4625 |
| Uniprot ID | MYH7_HUMAN |
| Immunogen Region | 1240-1340 aa |
| Immunogen Sequence | KAKANLEKMCRTLEDQMNEH RSKAEETQRSVNDLTSQRAK LQTENGELSRQLDEKEALIS QLTRGKLTYTQQLEDLKRQL EEEVKAKNALAHALQSARHD C |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1240-1340 of human MYH7/Beta-MHC (NP_000248.2). |
Additional Info
| Tissue Specificity | Both wild type and variant Gln-403 are detected in skeletal muscle (at protein level). |
| Function | Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. |
| Protein Name | Myosin-7Myosin Heavy Chain 7Myosin Heavy Chain Slow IsoformMyhc-SlowMyosin Heavy Chain - Cardiac Muscle Beta IsoformMyhc-Beta |
| Database Links | |
| Cellular Localisation | CytoplasmMyofibrilSarcomereThick Filaments Of The Myofibrils |
| Alternative Antibody Names | Anti-Myosin-7 antibodyAnti-Myosin Heavy Chain 7 antibodyAnti-Myosin Heavy Chain Slow Isoform antibodyAnti-Myhc-Slow antibodyAnti-Myosin Heavy Chain - Cardiac Muscle Beta Isoform antibodyAnti-Myhc-Beta antibodyAnti-MYH7 antibodyAnti-MYHCB antibody |
Information sourced from Uniprot.org