• Human colon wall stained with anti-SMMH antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of smooth muscle and vessel wall.

Anti-MYH11 antibody [SMMS‐1] (STJ180190)

SKU:
STJ180190

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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-MYH11 is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: SMMS‐1
Conjugation: Unconjugated
Isotype: IgG1/Kappa
Formulation: Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification: Affinity purified
Dilution Range: 1:100‐200
Storage Instruction: Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Gene Symbol: MYH11
Gene ID: 4629
Uniprot ID: MYH11_HUMAN
Specificity: Positive control: Transitional cell carcinoma
Immunogen: Crude human uterus extract
Tissue Specificity Smooth muscle.expressed in the umbilical artery, bladder, esophagus and trachea. Isoform 1 is mostly found in slowly contracting tonic muscles.
Function Muscle contraction.
Protein Name Myosin-11
Myosin Heavy Chain 11
Myosin Heavy Chain - Smooth Muscle Isoform
Smmhc
Database Links Reactome: R-HSA-3928663
Reactome: R-HSA-416572
Reactome: R-HSA-445355
Reactome: R-HSA-5625740
Reactome: R-HSA-5625900
Reactome: R-HSA-5627117
Reactome: R-HSA-5627123
Cellular Localisation Melanosome
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Thick Filaments Of The Myofibrils
Alternative Antibody Names Anti-Myosin-11 antibody
Anti-Myosin Heavy Chain 11 antibody
Anti-Myosin Heavy Chain - Smooth Muscle Isoform antibody
Anti-Smmhc antibody
Anti-MYH11 antibody
Anti-KIAA0866 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance