Anti-MYH11 antibody (1680-1979) (STJ112723)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MYH11 (1680-1979) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYH11 |
| Gene ID | 4629 |
| Uniprot ID | MYH11_HUMAN |
| Immunogen Region | 1680-1979 |
| Immunogen Sequence | ATAKENEKKAKSLEADLMQL QEDLAAAERARKQADLEKEE LAEELASSLSGRNALQDEKR RLEARIAQLEEELEEEQGNM EAMSDRVRKATQQAEQLSNE LATERSTAQKNESARQQLER QNKELRSKLHEMEGAVKSKF KSTIAALEAKIAQLEEQVEQ EAREKQAATKSLKQKDKKLK EILLQVEDERKMAEQYKEQA EKGNARVKQLKRQLEEAEEE SQRINANRRKLQRELDEAT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1680-1979 of human SMMHC/SMMHC/MYH11 (NP_001035203.1). |
Additional Info
| Tissue Specificity | Smooth muscle.expressed in the umbilical artery, bladder, esophagus and trachea. Isoform 1 is mostly found in slowly contracting tonic muscles. |
| Function | Muscle contraction. |
| Protein Name | Myosin-11Myosin Heavy Chain 11Myosin Heavy Chain - Smooth Muscle IsoformSmmhc |
| Database Links | Reactome: R-HSA-3928663Reactome: R-HSA-416572Reactome: R-HSA-445355Reactome: R-HSA-5625740Reactome: R-HSA-5625900Reactome: R-HSA-5627117Reactome: R-HSA-5627123 |
| Cellular Localisation | MelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage IvThick Filaments Of The Myofibrils |
| Alternative Antibody Names | Anti-Myosin-11 antibodyAnti-Myosin Heavy Chain 11 antibodyAnti-Myosin Heavy Chain - Smooth Muscle Isoform antibodyAnti-Smmhc antibodyAnti-MYH11 antibodyAnti-KIAA0866 antibody |
Information sourced from Uniprot.org